Carboxylic acid compound having condensed ring, salt thereof and pharmaceutical use thereof

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United States of America Patent

PATENT NO 5635527
SERIAL NO

08591537

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Abstract

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A novel carboxylic acid compound having a condensed ring, which is represented by the formula (I) ##STR1## wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, a pharmaceutical composition thereof and pharmaceutical use thereof. The novel carboxylic acid compound having a condensed ring and pharmacologically acceptable salt thereof of the present invention have superior GPIIb/IIIa antagonism in mammals inclusive of human; can be administered orally; have long life in blood and low toxicity; and show less side-effects. Accordingly, they are extremely useful for the prophylaxis and treatment of thrombotic diseases and other diseases.

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Patent Owner(s)

Patent OwnerAddress
WELFIDE CORPORATIONOSAKA-SHI OSAKA 541-0046

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ashimori, Atsuyuki Hirakata, JP 7 48
Ebisu, Hajime Hirakata, JP 6 49
Eda, Masahiro Hirakata, JP 11 230
Ikegawa, Ruriko Hirakata, JP 3 9
Imada, Teruaki Hirakata, JP 6 57
Inoue, Yoshihisa Hirakata, JP 99 714
Kosaka, Keigo Hirakata, JP 2 8
Maeda, Kazuhiro Hirakata, JP 159 2116
Mori, Fumio Hirakata, JP 49 434
Nakamura, Norifumi Hirakata, JP 20 339
Okada, Takehiro Hirakata, JP 27 350
Ono, Shinichiro Hirakata, JP 7 18
Wang, Feng Hirakata, JP 857 9908
Yoshida, Tomohiro Hirakata, JP 69 387

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