Secretory leukocyte protease inhibitor as an inhibitor of tryptase
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United States of America Patent
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May 27, 1997
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N/A
app pub date -
Sep 12, 1994
filing date -
Sep 12, 1994
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Expired
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Abstract
This invention concerns methods of treating mast-cell mediated conditions in mammals, the methods comprising administering to the mammals pharmacologically active fragments or muteins of SLPI; methods of treating asthma or allergic rhinitis in mammals, the methods comprising administering to the mammals SLPI or pharmacologically active fragments or muteins thereof; methods for inhibiting tryptase; methods for identifying inhibitors of tryptase; and certain fragments and muteins of SLPI.
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