Glycosylated steroid derivatives for transport across biological membranes and process for making and using same

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United States of America Patent

PATENT NO 5627270
SERIAL NO

08264488

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Abstract

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Novel glycosylated steroid derivatives for facilitating the transport of compounds across biological membranes, either in admixture or as conjugates, are disclosed. A novel process for efficient synthesis of these glycosylated steroid derivatives, using activated glycosyl sulfoxide intermediates is provided. Methods for the permeabilization of membranes and the enhancement of the activity of predetermined compounds are also provided.

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Patent Owner(s)

Patent OwnerAddress
TRUSTEES OF PRINCETON UNIVERSITYNEW SOUTH BUILDING 5TH FLOOR P O BOX 36 PRINCETON NJ 08544
TRANSCELL TECHNOLOGIES INC2000 CORNWALL ROAD MONMOUTH JUNCTION NJ 08852

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hatzenbuhler, Nicole T Kendall Park, NJ 7 45
Kahne, Daniel E Princeton, NJ 13 228
Kahne, Suzanne W Princeton, NJ 2 119
Sofia, Michael J Laurenceville, NJ 34 288

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