Processes for the production of 13-ether derivatives of milbemycins and novel intermediates therefor
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United States of America Patent
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Apr 29, 1997
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app pub date -
May 11, 1995
filing date -
Sep 1, 1992
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Abstract
An intermediate useful in the synthesis of milbemycin derivatives having an ether bond at the 13-position and which is represented by the general formula (IIId): ##STR1## wherein R represents a methyl group, an ethyl group, an isopropyl group or a sec-butyl group, and R.sup.5 and R.sup.6' each individually represents a hydrogen atom or a protecting group, and related precursors as well as to a process for producing these intermediates.
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