Method for identification of low/non-addictive opioid analgesics and the use of said analgesics for treatment of opioid addiction
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Apr 29, 1997
Issued Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Sep 21, 1992
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The present invention relates to a method of using a bioassay consisting of an electrophysiological method and a cell culture system of dorsal-root ganglion (DRG) neurons to screen and identify opioids with a high potential for use as 'low- or non-addictive' analgesics. Another aspect of the invention relates to a specific group of opioid alkaloids and analogues thereof identified by the bioassay of the invention for the unique ability to activate only inhibitory, but not excitatory, opioid receptor function, for use as low- or non-addictive analgesics. Another aspect of the invention relates to the specific use of etorphine or dihydroetorphine of the opioid alkaloid family as low- or non-addictive analgesics and for the treatment of opioid addiction.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully