Cloning and sequencing of the gene which codes for a new pilinic subunit of bordella pertussis
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United States of America Patent
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Apr 22, 1997
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app pub date -
Nov 4, 1994
filing date -
Dec 22, 1987
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Abstract
The cloning and sequencing of the gene which codes for a new pilinic subunit of Bordetella pertussis are described. The aminoacid sequence of the mature subunit, deduced from its necleotide sequence, is similar but not identical to that of the known pilins 2, 3 and 6. Polypeptides having the aminoacid sequence of the mature pilinic subunit or of regions thereof are particularly useful for the development of synthetic acellular vaccines against pertussis.
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