Derivatives of .beta., .beta.-dimethyl-4-piperidineethanamine as inhibitors of the cholesterol biosynthesis
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United States of America Patent
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Mar 25, 1997
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N/A
app pub date -
Oct 30, 1995
filing date -
May 17, 1993
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Expired
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Abstract
The present invention concerns .beta.,.beta.-dimethyl-4-piperidineethanamine compounds of the formula: ##STR1## (wherein groups R.sub.1 to R.sub.3 are defined as indicated in the description), and addition salts thereof. It also concerns a process for their preparation and their therapeutic use as inhibitors for the cholesterol biosynthesis, in particular as epoxysqualene cyclase inhibitors, for obtaining an as hypocholesterolemic, hypolipemic, antiatheromatic and/or antifungal drug.
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