Bisphosphonic acid derivatives as anti-arthritic agents
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United States of America Patent
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Feb 11, 1997
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N/A
app pub date -
Nov 28, 1994
filing date -
Aug 21, 1990
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Abstract
The bisphosphonates of formula (III) R.sub.2 --X--(CW).sub.m1 --CR.sub.3 R.sub.4 --CH.sub.2 --CM[PO--(OR.sub.1).sub.2 ].sub.2 (III) bicyclic bisphosphonates (V), and cyclic bisphosphonates (VII) are useful as antiarthritic agents and do not have the side effects of anti-arthritic agents which are prostaglandin synthetase inhibitors.
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