Autoantibodies which enhance the rate of a chemical reaction
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United States of America Patent
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Feb 11, 1997
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app pub date -
Jun 13, 1994
filing date -
Apr 25, 1989
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Abstract
Autoantibodies which enhance the rate of a chemical reaction of a substrate, processes for their preparation, their use and compositions thereof are disclosed. In particular, an autoantibody capable of catalyzing the hydrolysis of the peptide bond between amino acid residues Thr.sup.7 -Asp.sup.8, Arg.sup.14 -Lys.sup.15, Gln.sup.16 -Met.sup.17, Met.sup.17 -Ala.sup.18, Ala.sup.18 -Val.sup.19, Lys.sub.20 -Lys.sup.21, Lys.sup.21 -Tyr.sup.22 in the neurotransmitter vasoactive intestinal peptide (VIP) is disclosed.
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