Reagent for measuring direct bilirubin

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United States of America Patent

PATENT NO 5599661
SERIAL NO

08365158

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Abstract

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A reagent system and method are described for optically measuring direct bilirubin by the reaction of a bilirubin oxidase, oxidizing agent or diazonium salt, with the direct bilirubin, wherein a tetrapyrrole compound is provided in the presence of the bilirubin oxidase, oxidizing agent or diazonium salt. It is possible to accurately measure the direct bilirubin, which is known to increase considerably in the biological fluids of patients having obstructive jaundice, etc. The reagent system and method are useful in clinical settings, etc.

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Patent Owner(s)

Patent OwnerAddress
MITSUBISHI KAGAKU IATRON INCTOKYO 162-0812

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kojima, Masami Chiba-ken, JP 50 643
Kondo, Hitoshi Kyoto, JP 103 874
Kurosaka, Keisuke Kyoto, JP 7 19
Senba, Shoji Kyoto, JP 2 5
Suzuki, Hiroshi Chiba-ken, JP 997 14336

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