Local drug delivery film for periodontal treatment
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United States of America Patent
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Feb 4, 1997
Grant Date -
N/A
app pub date -
Feb 28, 1995
filing date -
Sep 1, 1992
priority date (Note) -
Expired
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Abstract
The present invention provides a local drug delivery film, which is characterized by comprising, as release control component, polymer mixture consistiong of polycaprolactone having molecular weight of 30,000-60,000 and polycaprolactone having molecular weight less than 1,000 in a ratio of 1:1-4:1, and as active component, periodontal therapeutic agent. The present local drug delivery film is prepared by admixing homogeneously active component with melted polymer mixture and pressing into film. And the present drug delivery film has excellent sustained release pattern and excellent treatment effect in oral disease with release amount 1.7 mg. which is 0.12% of prescription amount, 1400 mg. for adults during 7 days and provides the application stability into human body.
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