Sustained release of peptides from pharmaceutical compositions
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United States of America Patent
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Jan 21, 1997
Grant Date -
N/A
app pub date -
Mar 8, 1995
filing date -
Sep 2, 1994
priority date (Note) -
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Abstract
The invention features a method of administering a peptide to a patient and delivering the peptide continuously over an extended period of time of at least three days by obtaining a solid pharmaceutical composition including a soluble, gelable salt of the peptide and up to 30 percent, by weight, of a pharmaceutically acceptable, soluble, monomeric carrier, and parenterally administering the solid composition to the patient in one injection, wherein the solid composition automatically forms a gel after interaction with the patient's bodily fluids and releases the peptide continuously within the patient over an extended period of at least three days.
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