Halogenation of cephalexin with haloperoxidase from Rathayibacter biopuresis

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United States of America Patent

PATENT NO 5589354
SERIAL NO

08360149

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Abstract

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An enzyme preparation that exhibits cephalosporin haloperoxidase activity is isolatable from a microorganism species of the Rathayibacter genus. This enzyme preparation can convert cephalexin to a halogenated cephalosporin antibiotic in a single step. A particular, unique microorganism that can provide the cephalosporin haloperoxidase enzyme preparation is Rathayibacter biopuresis.

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Patent Owner(s)

Patent OwnerAddress
HEMOGLOBIN OXYGEN THERAPEUTICS LLC674 SOUDER ROAD SOUDERTON PA 18964

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Yung-Pin Columbia, SC 17 71
Shen, Yong-Qiang Revere, MA 4 3
Wong, Bing L Durham, NH 6 19

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