Delivery of exogenous DNA sequences in a mammal
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United States of America Patent
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Dec 3, 1996
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N/A
app pub date -
Mar 18, 1994
filing date -
Mar 21, 1989
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Abstract
Polynucleotide sequences, comprising DNA and RNA molecules can be directly administered, for example by injection, to tissues, such as muscle, and expressed as a protein, polypeptide or polypeptide. The polynucleotides can be contained within liposomes or the polynucleotides can free from association with transfection-facilitating proteins, viral particles, liposomal formulations, charged lipids and calcium phosphate precipitating agents.
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