Derivatives of indan-1,3-dione and indan-1,2,3-trione, methods of preparing them and therapeutic use thereof

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United States of America Patent

PATENT NO 5571843
SERIAL NO

08142479

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Abstract

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Therapeutic compounds having the formula: ##STR1## in which R.sub.2 and R.sub.3 independently denote H, C.sub.1 -C.sub.4 alkoxy or OH and (A, B)=(oxygen, oxygen) in which case one out of R and R.sub.1 denotes OH, halogen, secondary amino or tertiary amine and the other denotes NHNHCONHR.sub.4 or R and R.sub.1 together denote .dbd.N--NH--CX--NHR.sub.5, .dbd.N--NH--CX--N(phenyl).sub.2, .dbd.N--NH--CX--NH--NH--R.sub.5, .dbd.N--NH--C(SCH.sub.3).dbd.N--R.sub.6 or .dbd.N--N.dbd.C(SCH.sub.3)--NH--R.sub.6 ; or (A, B)=(N--OH, oxygen) in which case R and R.sub.1 together form .dbd.N--NH--CX--NHR.sub.5 or .dbd.N--NH--CX--N(phenyl).sub.2 ; or (A, B)=(N--NH--CX--NHR.sub.5, oxygen) in which case R and R.sub.1 together form .dbd.N--NH--CX--NHR.sub.5 ; or (A, B)=(N--OH, N--OH) in which case R and R.sub.1 together form .dbd.N--NH--CX--NHR.sub.5 or .dbd.N--NH--CX--N(phenyl).sub.2.

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Patent Owner(s)

Patent OwnerAddress
INNOTHERA10 AVENUE PAUL VAILLANT COUTURIER 94110 ARCUEIL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cugnon, de Sevricourt Michel P Moult, FR 2 3
Dacquet, Catherine G Paris, FR 2 3
Finet, Michel A Fresnes, FR 2 3
Le, Marquer Florence J Paris, FR 2 3
Robba, Max F Paris, FR 6 16
Tembo, Norbert O Cergy St Christophe, FR 2 3
Torregrosa, Jean-Luc Saint-Denis, FR 4 14
Yannic-Arnoult, Sylvie J Grigny, FR 2 3

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