Indocarbocyanine-linked phosphoramidites
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United States of America Patent
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Sep 17, 1996
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N/A
app pub date -
Jun 24, 1994
filing date -
Jan 22, 1993
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Abstract
A chemical compound of the following formula is disclosed ##STR1## where R is one of H, trityl, 4-0-monomethoxytrityl, 4,4'-O-dimethoxytrityl, or acyl groups and R may be used as a protecting group or is an H; R.sup.1 is a phosphoramidite; R.sup.11 is one of H or lower alkyl groups; R.sup.111 is one of H or lower alkyl groups; R.sup.4 is one of H, lower alkyl, acyl, or (CH.sub.2).sub.p COO(CH.sub.2).sub.q CH.sub.3 where p is an integer from 0 to 4 and q is an integer from 0 to 4; R.sup.5 is one of H, lower alkyl, acyl, or (CH.sub.2).sub.p COO(CH.sub.2).sub.q CH.sub.3 where p is an integer from 0 to 4 and q is an integer from 0 to 4; n is an integer from 0 to 10; m is an integer from 0 to 10; and r is 1, 2, or 3.
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