Anti-tumor platinum complexes
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United States of America Patent
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Aug 20, 1996
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N/A
app pub date -
Feb 27, 1995
filing date -
Feb 27, 1995
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Expired
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Abstract
Platinum complexes, having anti-tumor activity, which include at least one functional ketone group or aldehyde, optionally conjugated as a linkable hydrazone complex. The functional ketone and aldehyde groups and the functionalized hydrazone complexes are linkable to antibodies, proteins, peptides and compounds having free amine, hydrazine or hydrazide functionality. Such agents are useful as targeted site-specific or disease specific chemotherapeutic agents.
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