Radial flow assay, delivering member, test kit, and methods

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United States of America Patent

PATENT NO 5547833
SERIAL NO

08177733

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Abstract

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A delivering member for filtering and delivering a sample to a test assay surface includes a prefilter having a sample receiving surface and a surface for delivering a sample to a test assay surface. The prefilter includes a diffusing material on its receiving surface for rapidly and evenly diffusing a sample across the prefilter receiving surface. In this way, a sample may be rapidly and evenly delivered to a test assay surface. A test assay solid phase has a surface including an area carrying an immobilized species and an area free of immobilized species. When a sample is applied to the surface, followed by application of a labeled species, the evenness of distribution of the labeled species is indicative of the evenness of application of the sample. A kit includes a delivering member and an assay surface.

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Patent Owner(s)

Patent OwnerAddress
CREDITANSTALT BANKVEREINTWO GREENWICH PLAZA GREENWICH CT 06880

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Denham, Lilibeth K Cambridge, MA 2 26
Dorval, Brent L Douglas, MA 3 50
Klibanov, Alexander M Newton, MA 57 1963

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