Cyclosporin containing powder composition

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United States of America Patent

PATENT NO 5543393
SERIAL NO

08347137

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Abstract

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The present invention relates to a cyclosporin-containing powder composition which comprises cyclosporin, a non-ionic hydrophilic surfactant and a porous carrier. In addition, the present invention relates to a method for preparing the cyclosporin-containing powder composition which comprises dissolving cyclosporin and a non-ionic hydrophilic surfactant in an organic solvent, adding a porous carrier to the resulting solution and then evaporating the organic solvent from the mixture. The powder composition of the present invention is stable and does not require a special manufacturing technique when it is formulated. In addition, since the powder composition of the present invention does not contain an organic solvent, the necessity of a special package is excluded. Furthermore, the composition of the present invention provides an improved bioavailability which results in decrease of a single dosage, and therefore, can contribute to the alleviation of the side effects associated with cyclosporin.

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Patent Owner(s)

  • CHONG KUN DANG CORP.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kim, Jung W Seoul, KR 2 83
Min, Kyeong B Seoul, KR 1 69
Park, Joon K Kyeonggi-do, KR 1 69
Shin, Hee J Kyeonggi-do, KR 2 490

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