Imidazolinoxyl derivatives

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United States of America Patent

PATENT NO 5536744
SERIAL NO

08363614

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Abstract

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This invention offers the compounds which exhibit a coronary blood vessel dilating action which is long-acting. (Constitution) Novel imidazolinoxyl derivatives represented by a general formula (1). A compound A in which R is COOH is given in an example. ##STR1## (Merit) The compounds of the present invention can be directly administered, after diluting to a suitable concentration with a phosphate buffer or the like, to blood vessel which is required to be relaxed and dilated whereby a significant and long-acting relaxing action is resulted though, in a blood flow, they are quickly inactivated and excreted and no side effect is noted.

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Patent Owner(s)

Patent OwnerAddress
DONJINO LABORATORIESTABARU 2025-2 MASHIKI-MACHI KAMIMASHIKI-GUN KUMATO 861-22

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akaike, Takaaki Kumamoto, JP 21 27
Katayama, Yoshiki Mashiki-machi, JP 35 239
Maeda, Hiroshi Kumamoto, JP 366 3334
Okumura, Ken Kumamoto, JP 7 48
Sasamoto, Kazumi Mashiki-machi, JP 8 78
Sato, Keizo Kumamoto, JP 18 81
Tsunoda, Ryusuke Kumamoto, JP 1 1

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