Compositions comprising ONCONASE(.TM.) and cisplatin, melphalan, or doxorubicin HCl
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United States of America Patent
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Jun 25, 1996
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app pub date -
Aug 1, 1994
filing date -
Apr 6, 1988
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Abstract
A pharmaceutical known by the trademark ONCONASE, as described in pending commonly owned application application Ser. No. 07/436,141 filed Nov. 13, 1989, is combined with drugs sold under the names cisplatin, Melphalan and Doxorubicin HCl. The combinations of ONCONASE with these drugs has unexpected bioactivity in vitro against OVCAR-3 human ovarian adenocarcinoma cells.
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