Carboxymethylidenecycloheptimidazole derivatives, method of manufacturing the same and therapeutic agents containing these compounds
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United States of America Patent
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Jun 18, 1996
Grant Date -
N/A
app pub date -
Jul 29, 1994
filing date -
Jul 30, 1993
priority date (Note) -
Expired
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Abstract
New therapeutic agent of carboxymethylidenecycloheptimidazole derivatives and method for the manufacture thereof are disclosed, which are represented by the following formula or its alkali addition salts ##STR1## (wherein R.sub.1 represents a lower alkyl; R.sub.2 represents H or isopropyl group; R.sub.3 represent H, a lower alkyl or --C(CH.sub.3)H--OCOOR.sub.4 (R.sub.4 is a lower alkyl or cyclohexyl) and .dbd.CHCOOR.sub.3 is substituted group at 4 or 8 position; A represents ##STR2## These compounds are useful as anti-hypertensive, anti-congestive heart failure agents and intraocular pressure lowering agents.
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