Dry and Porous galenic form based on plants, its method of preparation and its applications
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United States of America Patent
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Jun 18, 1996
Issued Date -
N/A
app pub date -
Apr 21, 1994
filing date -
Dec 23, 1991
priority date (Note) -
Expired
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Abstract
Solid compositions based on plants, capable of being converted to a dry and porous galenic form (lyophilized or equivalent form) which is undivided or powdered. Said dry and porous galenic form comprises a solid composition II consisting of a solid composition I composed of: (A) one or more of the plants' active principles included in a homogeneous suspension of fresh or dry plants obtained by (a) cleaning and/or drying of the plant or part of the plant, (b) cryocomminution at a temperature below 0.degree. C. until a particle size of less than about 100 .mu.m is obtained, (c) immersion of the particles for a suitable time in at least one appropriate solvent, (d) separation of the liquid phase and the solid phase of the suspension obtained, (e) expression of the solid phase obtained in (d) by cold pressing, and (f) mixing of the liquid phase obtained in (d) and the expressed liquid obtained in (e), and (B) at least one absorption promoter with a sequestering action, said mixture (A+B) being dried by removal of the solvent; and (C) at least one absorption promoter selected from surfactants, said composition II being lyophilized and optionally associated with excipients which are suitable from a pharmaceutical point of view.
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