Apparatus and process for determining the sources of biomagnetic activity

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United States of America Patent

PATENT NO 5526811
SERIAL NO

08078451

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Abstract

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An apparatus and process for making biomagnetic measurements of a biological organism permits the internal sources of the activity to be identified. An array of dipole sources is identified by providing a plurality of biomagnetic sensors disposed at locations external to the biological organism, measuring a measured biomagnetic response at each of the sensors, and amplifying and filtering the measured biomagnetic response. A solution of dipole sources within the biological organism is determined by forward calculating a computed biomagnetic response at each of the sensors resulting from the biomagnetic activity of a plurality of dipole sources, each of which dipole sources contributes a normalized total signal strength at the sensors, and solving for the strengths of each of the dipole sources by a minimum norm estimation procedure. Convergence on the solution is aided by iteratively removing from the determination those apparent sources that contribute only a small portion of the signal strength, and then resolving the resulting relationship.

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Patent Owner(s)

Patent OwnerAddress
YNI LIMITEDTHE BIOCENTRE YORK SCIENCE PARK YORK YO10 5DG

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lypchuk, Tanya San Diego, CA 1 50

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