Method for fixing a biological preparation
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United States of America Patent
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Jun 11, 1996
Grant Date -
N/A
app pub date -
Dec 20, 1994
filing date -
Dec 20, 1993
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Biological preparations or specimens are treated for a subsequent microscopic inspection. For this purpose it is necessary that the inner structure that is to be studied does not change prior to and during inspection. It is thus necessary to subject the specimens to a chemical and/or mechanical pretreatment for increasing the permeability of the specimen surface to a fixation substance in the form of an aqueous solution that contains an aldehyde fixation agent, preferably a highly volatile fixation agent or substance. The exposure of the specimens to the fixation substance takes place by immersion and/or spraying and/or fumigation. The fixation agent is preferably volatile and in the form of an aldehyde proportion of about 5% by volume or of an acrolein proportion of about 10% by volume.
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