Pseudopeptide bradykinin receptor antagonists
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United States of America Patent
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May 28, 1996
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N/A
app pub date -
Oct 8, 1992
filing date -
Oct 8, 1992
priority date (Note) -
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Abstract
The invention relates to peptides of up to 10 amino acids that are synthesized by substituting at least one of the bradykinin amino acids found in positions 2, 3, 4 and 5 of the bradykinin peptide with a fatty acid amine. The modified bradykinin peptides produced confer increased resistance to enzymatic degradation and/or tissue specificity. The invention also relates to pharmaceutical preparations and processes of treatments using the modified bradykinin peptides.
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