Elastomeric polypeptide matrices for preventing adhesion of biological materials
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United States of America Patent
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May 21, 1996
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N/A
app pub date -
Jun 7, 1995
filing date -
May 20, 1994
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Abstract
The invention provides a bioelastomer comprising tetrapeptide and/or pentapeptide monomeric units of the formula: R.sub.1 PGR.sub.2 G.sub.n wherein R.sub.1 is a peptide-producing residue of alanine or glycine; P is a peptide-producing residue of proline; G is a peptide-producing residue of glycine; R.sub.2 is a peptide-producing residue of glycine or alanine; and n is 0 or 1. In a further aspect of the invention, a method is provided for preventing adhesion of biological materials, such as protein, cells, and tissues, by forming a protective layer between a first surface and a second surface using the bioelastomer.
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