Carbocyclic adenosine analogs useful as immunosuppressants
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United States of America Patent
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May 7, 1996
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May 12, 1994
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Sep 14, 1990
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Abstract
This invention relates to carbocyclic adenosine compounds of the formula (1) ##STR1## wherein the hydroxy substituent on the cyclopentanyl ring is in the CIS configuration relative to the bicyclic substituent, Y.sub.3, Y.sub.7, Y.sub.8 and Y.sub.9 are each independently nitrogen or a CH group, Q is NH.sub.2, halogen or hydrogen, and Z is hydrogen, halogen, or NH.sub.2 ; or a pharmaceutically-acceptable salt thereof, and to their use as immunosuppressants.
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