Compounds containing a fused bicycle ring and processes therefor
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United States of America Patent
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Apr 16, 1996
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app pub date -
May 5, 1994
filing date -
Jun 15, 1993
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Abstract
Compounds of the formula ##STR1## wherein X is O or S--(O).sub.t ; n is one or two; m is zero or one; Y is CH.sub.2, O, or S--(O).sub.t provided that Y is O or S--(O).sub.t only when m is one; and A is ##STR2## are dual inhibitors of NEP and ACE. Compounds wherein A is ##STR3## are selective ACE inhibitors. Also disclosed are methods of preparation and intermediates.
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