Method of determining blood coagulation factor XIII activity and kit of reagents for the determination

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United States of America Patent

PATENT NO 5508202
SERIAL NO

08232221

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Abstract

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An accurate, rapid and simple method of determining blood coagulation factor XIII activity and a kit of reagents therefor are provided. A sample and a fibrin precipitation inhibitor are mixed, or a sample, fibrinogen and a fibrin precipitation inhibitor are mixed; a thrombin solution is added; the fibrin coagulation time is measured in the presence of calcium ion; and the coagulation time is compared with the normal coagulation time. The kit for the determination comprises thrombin, calcium ion and a fibrin precipitation inhibitor, and may be combined with fibrinogen.

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Patent Owner(s)

Patent OwnerAddress
NIPPON SHOJI KAISHA LTD2-9 KOKUMACHI 2-CHOME CHUO-KU OSAKA 540

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Enomoto, Masayasu Takatsuki, JP 9 72
Yamaguchi, Masahiro Suita, JP 178 2408

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