Cross-linked polyethylene oxide coatings to improve the biocompatibility of implantable medical devices
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United States of America Patent
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Apr 16, 1996
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N/A
app pub date -
Nov 16, 1994
filing date -
Nov 16, 1994
priority date (Note) -
Expired
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Abstract
Polyethylene oxide (PEO) coatings providing improved biocompatibility for implantable medical devices are disclosed. The PEO coatings comprise functionalized end-capped PEO which is attached at one end to the medical device. The PEO compounds are then exposed to a high energy source for a time sufficient to cause the PEO compounds to form a cross-linked, insoluble network. These PEO coatings are able to survive ethylene oxide sterilization procedures with minimal loss of protein or cell repulsion ability.
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