A process for producing legionella specific antibiotic using Streptomyces sp. AL91
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United States of America Patent
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Apr 2, 1996
Issued Date -
N/A
app pub date -
Jun 6, 1995
filing date -
Sep 14, 1994
priority date (Note) -
Expired
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Abstract
A Legionella specific antibiotic AL072, a Streptomyces sp. AL91 producing the antibiotic, and a process for producing the antibiotic are disclosed. Further, the antibiotic compound has a specified formula. The formula is ##STR1## In addition the process also includes extraction of a culture broth provided by cultivating the microorganism Streptomyces sp. AL91, accession number KCCM 10055, with isopropyl alcohol and ethyl acetate to obtain an extract containing the antibiotic compound. The compound is then isolated from the extract by chromatography on a column filled with octadecyl silica gel and also by high pressure liquid chromatography.
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