Polynucleotide encoding T-cell epitopes of the protein TraT
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United States of America Patent
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Mar 19, 1996
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Mar 16, 1993
filing date -
Sep 18, 1990
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Abstract
T-cell epitopes of or derived from the TraT protein of E. coli have been identified and used in the preparation of complexes with immunogens to enhance or provide immune responses to the immunogens. The complexes can be prepared directly, by chemical linkage, or as fusion proteins. In the latter context, polynucleotides encode a fusion protein which a transformed host can express. The fusion proteins may be expressed intracellularly or exported to and expressed on the surface of the transformant host.
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