Device for analyzing the metabolism of cells

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United States of America Patent

PATENT NO 5489515
SERIAL NO

08353268

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A device for analyzing the metabolism of cells includes a supporting base which carries a pH measuring electrode, a control electrode designed for proton exchange with the liquid, a reference electrode, and a counterelectrode, and which, together with at least one other part, confines a hollow space containing the cells and a liquid. The electrodes are connected to electronic circuit elements. In the course of an analysis the pH value of the liquid is determined by means of the pH measuring electrode and the reference electrode. Between the control electrode and the counterelectrode an electric current is passed through the liquid and controlled such that the pH of the liquid is maintained at a constant preset value beneficial to the cells, by proton exchange with the control electrode. In addition, the amount of charge required for generating the current during the measuring period is determined to obtain a measure for the intensity of the metabolic process and thus for the vitality of the cells.

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Patent Owner(s)

Patent OwnerAddress
AVL MEDICAL INSTRUMENTS AG8207 SCHAFFHAUSEN

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hatschek, Rudolf Fribourg, CH 2 35
Heitz, Erich W F Schaffhausen, CH 2 32

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