Cyclosporine assay
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United States of America Patent
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Jan 2, 1996
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app pub date -
Jan 12, 1993
filing date -
Sep 7, 1988
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Abstract
A process for determining the concentration of cyclosporine in a sample, which comprises adding to the sample a predetermined amount of an isomerase which isomerizes N-terminal peptide to proline, then measuring the enzyme-catalyzed inhibition of the isomerization of a proline-containing substrate, and determining the concentration or cyclosporine from a calibration curve.
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