Insulin analog formulations

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United States of America Patent

PATENT NO 5474978
SERIAL NO

08260634

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention discloses a human insulin analog hexamer complex and formulations. More specifically, the present invention relates to various parenteral formulations, which comprise: human insulin analogs in a hexamer conformation, zinc ions, and at least three molecules of a phenolic derivative selected from the group consisting of m-cresol, phenol, or a mixture of m-cresol and phenol. The formulation provides a rapid onset of action.

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Patent Owner(s)

Patent OwnerAddress
ELI LILLY AND COMPANYLILLY CORPORATE CENTER PATENT DIVISION INDIANAPOLIS IN 46285

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bakaysa, Diane L Indianapolis, IN 2 117
Brems, David N Indianapolis, IN 4 125
Frank, Bruce H Indianapolis, IN 14 735
Havel, Henry A Indianapolis, IN 8 291
Pekar, Allen H Indianapolis, IN 4 131

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