Method for producing protein-synthetic polymer conjugate and said conjugate produced thereby
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United States of America Patent
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Dec 5, 1995
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N/A
app pub date -
Mar 18, 1994
filing date -
Mar 18, 1994
priority date (Note) -
Expired
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Abstract
A method for producing an ester of a protein by an esterification reaction of an aqueous solution, fine powder or suspension of a protein having free carboxyl groups with an excess amount of polyfunctional alcohol to esterify the protein; a method for producing a protein-synthetic polymer conjugate from said ester by utilizing a hydroxyl or unsaturated group of a polyfunctional alcohol present in the esterified portion of the protein; and a protein-synthetic polymer conjugate produced thereby.
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