Substituted pyrazolyl compounds and methods employing such compounds
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United States of America Patent
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Nov 28, 1995
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app pub date -
Feb 3, 1995
filing date -
Feb 3, 1995
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Abstract
This invention pertains to novel substituted pyrazolyl compounds useful as intravenous anesthetics represented by the Formula: ##STR1## including geometric and optically active isomeric forms, and the pharmaceutically acceptable acid addition salts thereof, wherein: one of Y and Z is nitrogen, and the other is CH; R.sub.1 is hydrogen or lower-alkyl; R.sub.2 and R.sub.3 are selected from the group consisting of hydrogen, --CHO, lower-alkylcarbonyl, lower-alkoxy carbonyl, lower-alkylaminocarbonyl, lower-alkyl, lower-alkenyl, lower-alkoxy-lower-alkenyl, lower-alkylcarbonyloxymethyl, substituted and unsubstituted heterocyclic rings, and substituted or unsubstituted aryl groups, wherein the symbol * represents a carbon atom which may be asymmetric and at least one of R.sub.2 and R.sub.3 is other than hydrogen.
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