Tetrahydroprotoberberine quaternary ammonium compounds useful in for treating arrhythmia
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United States of America Patent
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Nov 28, 1995
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N/A
app pub date -
Oct 31, 1994
filing date -
Oct 21, 1991
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Abstract
A tetrahydroprotoberberine quaternary ammonium compound represented by the formula: ##STR1## wherein R.sub.1, R.sub.2, R' and X are as defined in the specification. A method of preparing the compound is provided. The compounds can suppress arrhythmia and ventricular fibrillation, protect against myocardial ischemia, and can be conveniently orally administered.
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