Acellular red blood cell substitute

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United States of America Patent

PATENT NO 5464814
SERIAL NO

08203505

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A process is disclosed for the preparation of an essentially tetramer-free, essentially stroma-free, cross-linked, polymerized, pyridoxylated hemoglobin which comprises separating red blood cell stroma from blood by means of heat treating step to remove stromal contaminants and filtration or centrifugation or both, pyridoxylating, polymerizing, and removing essentially all of the remaining unmodified tetramer.

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Patent Owner(s)

Patent OwnerAddress
OPK BIOTECH LLC11 HURLEY STREET CAMBRIDGE MA 02141

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
De, Woskin Richard E Mount Prospect, IL 9 226
Gould, Steven A Highland Park, IL 9 225
Moss, Gerald S Highland Park, IL 8 225
Rosen, Arthur L Wilmette, IL 11 325
Sehgal, Hansa Flossmoor, IL 8 225
Sehgal, Lakshman R Flossmoor, IL 43 528

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  • 37 Citation Count
  • A61K Class
  • 91.24 % this patent is cited more than
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges206994325120553912156652001 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +05010015020025030035040045050055060065070075080085090095010001050

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