1-.beta.-methyl-2-thiolic carbapenem derivatives
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United States of America Patent
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Oct 31, 1995
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app pub date -
Nov 19, 1993
filing date -
Jun 15, 1993
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Abstract
The present invention relates to new 1-.beta.-methyl-2-thiolic carbapenem derivatives represented by the following general formula (I) and producing method thereof. ##STR1## The above-mentioned compound is very stable against DHP-1 enzyme due to effective shielding of carbapenem ring structually and is highly effective in both gram-positive and gram-negative microorganism, especially has a remarkable effect on the Pseudomonas aeruginosa known as a disease germ having strong resistance.
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