Strand displacement amplification

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United States of America Patent

PATENT NO 5455166
SERIAL NO

07819358

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Abstract

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This invention relates a nucleic acid target amplification and detection method which operates at a single temperature and makes use of a polymerase in conjunction with an endonuclease that will nick the polymerized strand such that the polymerase will displace the strand without digestion while generating a newly polymerized strand.

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Patent Owner(s)

Patent OwnerAddress
BECTON DICKINSON AND COMPANY1 BECTON DRIVE FRANKLIN LAKES NJ 07417 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Walker, George T Chapel Hill, NC 27 1867

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