N-acyl-4-phenyl-pyrrolidin-2-ones and method for preparing
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United States of America Patent
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Aug 15, 1995
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Jan 13, 1994
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Jan 31, 1990
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Abstract
The invention is directed to N-acetyl-4-phenyl-pyrrolidin-2-ones, which, because of their pronounced cerebroprotective effect in human medicine, can be used for the prophylaxis and treatment of cerebral functional disorders. Pursuant to the invention, these compounds are synthesized by reacting 4-phenyl-pyrrolidin-2-ones with a reactive derivative of a carboxylic acid, or by cyclizing N-acylaminobutyric acid derivatives.
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