Monoclonal antibodies against human Tumor Necrosis Factor .alpha.
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United States of America Patent
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Jul 25, 1995
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N/A
app pub date -
Dec 13, 1991
filing date -
Dec 28, 1990
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Abstract
A monoclonal antibody is provided which is able to neutralize both human TNF .alpha. and TNF .beta., or a binding fragment thereof. A stable hybridoma cell line and progeny thereof are also provided which secrete such a monoclonal antibody. The monoclonal antibody or a fragment thereof may be used to detect the content of human TNF in a sample of body fluid.
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