Tricyclic carbapenem compounds, methods of preparation and methods of use

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United States of America Patent

PATENT NO 5426104
SERIAL NO

08107848

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Abstract

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Compounds of general formula (I) ##STR1## in which R.sub.1 represents a hydrogen atom or a hydroxyl protecting group, R.sub.2 represents a hydrogen atom or a carboxyl protecting group, and R.sub.3 represents the group N(R.sub.4)--CH.dbd.NR.sub.5 wherein R.sub.4 represents a hydrogen atom and R.sub.5 represents a hydrogen atom; and salts, metabolically labile esters and solvates thereof and a process for their production. The compounds of formula (I) are either antibacterial agents and or useful intermediates for the preparation of antibacterial agents.

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Patent Owner(s)

Patent OwnerAddress
GLAXO SPAVIA ALESSANDRO FLEMING 2 37100 VERONA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Donati, Daniele Verona, IT 13 49
Perboni, Alcide Verona, IT 14 24
Tarzia, Giorgio Verona, IT 36 172

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