Fermentation method and fermentor
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United States of America Patent
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Jun 20, 1995
Grant Date -
N/A
app pub date -
Oct 23, 1992
filing date -
Oct 23, 1992
priority date (Note) -
Expired
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Abstract
A method for aerobic production of microbial cells and/or cell metabolites in a fermentation vessel having at least a riser and at least a downcomer. The method is especially useful to conduct high cell density fermentation processes and involves the controlled addition of an antifoam agent, for maintaining a predetermined and relatively high gas hold up within the fermentor. Also disclosed are various types of fermentors for practicing the method of the invention.
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