Process for producing ortho-isopropylated phenol derivatives

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United States of America Patent

PATENT NO 5414156
SERIAL NO

08245091

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Abstract

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This invention relates to the process for producing ortho-isopropylated phenol derivatives having following general formula (VIII). ##STR1## (in the above formula, R.sub.1 is a hydrogen or a low alkyl group of C.sub.1 -C.sub.4) A process for producing ortho-isopropylated phenol derivatives (VIII) of the present invention is characterized by obtaining position isomer desired by means of Claisen rearrangement of phenyl allyl ether without catalyst in atmosphere, and then obtaining only one isomer by oxidation and reduction of the above-obtained position isomer. According to the present invention, ortho-alkylated phenol derivatives (VIII) having high purity at low temperature and low pressure can be prepared without producing a by-product and requirement of the complicated separation procedure.

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Patent Owner(s)

  • DONG KOOK PHARMACEUTICAL CO., LTD.;KWON; KI-BEOM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cho, Jung H Seoul, KR 3 65
Kim, Wan S Seoul, KR 14 54
Nam, Kie H Seoul, KR 1 5

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