New 4'-epi-4'-amino anthracyclines
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United States of America Patent
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May 2, 1995
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app pub date -
Jan 6, 1993
filing date -
Feb 7, 1989
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Abstract
Anthracycline glycosides having the general formula 1 and 2: ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen, fluorine, hydroxy or amino; R.sub.2 and R.sub.3 represent hydroxy or one of R.sub.2 and R.sub.3 is a hydrogen atom, a nitro or an amino group and the other of R.sub.2 and R.sub.3 is a HYDROXY group, exhibit activity against LoVo and LoVo/Dx in vitro.
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