Process for obtaining an antigenic reagent useful for the indirect determination of Salmonella typhi
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United States of America Patent
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Apr 11, 1995
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N/A
app pub date -
Mar 21, 1991
filing date -
May 10, 1990
priority date (Note) -
Expired
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Abstract
The invention described herein consists of a process for preparing an antigenic reagent useful for the indirect determination of Salmonella typhi, the organism that is the causal agent of typhoid fever (TF). The invention consists on the following steps: to grow Salmonella typhi in a culture medium, characterized by containing a free-iron chelator, which generates a specific S. typhi outer membrane protein (OMP) pattern, OMPs that are used as a selective antigen for the detection of specific serum antibodies, by an immunoassay technique (ELISA).
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