Method, composition and device for measuring the ionic strength or specific gravity of a test sample
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United States of America Patent
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Apr 4, 1995
Issued Date -
N/A
app pub date -
Mar 25, 1994
filing date -
Feb 19, 1993
priority date (Note) -
Expired
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Abstract
A method, composition and test device for determining the ionic strength or specific gravity of a test sample are disclosed. The method utilizes a test device comprising a test pad, wherein the test pad includes a carrier matrix incorporating a reagent composition capable of producing a detectable and measurable response that correlates to the ionic strength and the buffer capacity, and therefore the specific gravity, of the test sample. The reagent composition, comprising a strong polyelectrolyte, an indicator comprising: (i) a dye that is metachromatic and sensitive to pH changes, or (ii) or a combination of metachromatic dye and a pH indicator dye, in a suitable carrier, and buffered at a pH of 3 or less, is incorporated into a carrier matrix to provide a test pad of a device useful in an ionic strength or specific gravity assay of a test sample.
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